Zachary J. Brown, DO is an Assistant Professor of Surgery within the Division of Surgical Oncology at NYU Langone Health and the Perlmutter Cancer Center. Dr Brown has a special interest in treating patients with advanced or metastatic cancers originating from the appendix, colon, rectum, small intestine, stomach and peritoneal surface. As a board-certified surgical oncologist, he is an expert in treating patients with a method known as cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).

CRS is a method of eliminating all visible tumor from the abdomen often requiring removal of the lining of the abdomen (peritoneum) and any involved organs. CRS is often followed by HIPEC which is the delivery of heated chemotherapy into the abdomen which aids in treating the cancer cells we cannot see or remove by CRS. With this treatment, we hope to offer patients improved survival that might not be possible with standard chemotherapy. Dr Brown takes a personalized approach to treat patients keeping their individual goals in mind and educating patients about their disease process so they may make informed decisions. He wants to give patients a sense of hope and emphasize to them that they are not defined by their disease.
In addition to treating patients, Dr Brown believes in the importance of cancer research to improve outcomes for both current patients as well as future ones. Dr Brown has authored over sixty peer-reviewed articles and six book chapters in authoritative journals such as JAMA Surgery, Journal of the American College of Surgeons, British Journal of Surgery, Annals of Surgical Oncology, Journal of Surgical Oncology, Gastroenterology, Journal for ImmunoTherapy of Cancer, and Cancer Cell. He continues to publish and present nationally and is an active committee member in the Society of Surgical Oncology. Dr Brown’s research is centered on the use of regional therapies, such as HIPEC, to treat patients with advanced cancers in order to better understand peritoneal disease which may lead to innovative therapies. He is focused on bringing new therapies and clinical trials to patients with peritoneal metastases to offer hope to patients who may be out of standard treatment options.
Prior to joining NYU, Dr Brown completed his general surgery residency at Rutgers Robert Wood Johnson Medical School as well as fellowships in Tumor Immunology and Surgical Oncology at the National Cancer Institute, National Institutes of Health (NIH/NCI) and a fellowship in Complex General Surgical Oncology at The Ohio State University and The James Cancer Hospital where he received specialized training in treating patients with advanced and metastatic cancers. Dr Brown enjoys working within a multidisciplinary team at NYU and the Perlmutter Cancer Center to provide the best comprehensive cancer care to his patients.

https://nyulangone.org/locations/hyperthermic-intraperitoneal-chemotherapy-program