Loma Linda Hospital
11370 Anderson St.
Loma Linda, CA 92354

The only cancer treatment center in the region that performs hyperthermic intraperitoneal chemotherapy

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a treatment option for patients with peritoneal spread of cancers arising from the appendix, colon and stomach, peritoneal mesothelioma and primary peritoneal malignancy.

HIPEC is the chemotherapy component of a surgical procedure called Cytoreductive Surgery (CRS) involving the removal of all the tumor masses and the affected abdominal wall lining (peritoneum) in the operating room. The surgery is immediately followed by the delivery of heated chemotherapy directly into the abdominal cavity via special catheters and heated perfusion pumps.

The chemotherapy agents are allowed to bathe the abdominal cavity for up to 90 minutes. Then, they are removed and the abdomen is flushed out with sterile solution.

For certain types of appendiceal cancer, cytosurgery with HIPEC is the only treatment required to adequately treat the cancer.

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HIPEC at Loma Linda Hospital

HIPEC is an alternative and innovative method of delivering chemotherapy, which is commonly used to treat many types of cancer, to the body. Unlike traditional chemotherapy that is delivered intravenously, HIPEC delivers chemotherapy directly into the abdomen making it a good option for cancers that originated in or have spread to the abdominal cavity. How does HIPEC work? First, your surgeon removes any visible tumors from the abdomen. Next, HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon. This is because the chemotherapy circulates inside the abdomen, allowing it to reach more places. The goal of HIPEC is to prevent these cells from growing into new tumors and causing

How does HIPEC work?

First, your surgeon removes any visible tumors from the abdomen. Next, HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon. This is because the chemotherapy circulates inside the abdomen, allowing it to reach more places. The goal of HIPEC is to prevent these cells from growing into new tumors and causing First, your surgeon removes any visible tumors from the abdomen. Next, HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon. This is because the chemotherapy circulates inside the abdomen, allowing it to reach more places. The goal of HIPEC is to prevent these cells from growing into new tumors and causing the cancer to return.

What are the benefits of HIPEC procedures?

  • HIPEC allows for a higher concentration of chemotherapy to be delivered into the abdomen more effectively and safer than standard chemotherapy, which is delivered intravenously.
  • This type of chemotherapy is best at killing cancer cells that are too small to be seen with the naked eye.
  • Chemotherapy delivered through HIPEC causes fewer side effects than intravenous chemotherapy. This is because the high concentrations of chemotherapy solution are unable to cross what is known as the peritoneal plasma barrier.
  • Experts say that pairing surgery and HIPEC together may be more beneficial than chemotherapy alone.

Am I a candidate for HIPEC?

Typical HIPEC patients are those with certain Stage IV abdominal cancers. Many are seeking an alternative to traditional chemotherapy or radiation therapy, as these options offer limited success treating advanced abdominal cancers. Patients also may have been told that no other treatment will work, but are still hoping to find a solution.