University of Miami Hospital
1400 NW 12th Ave.
Miami, FL 33136

 

 

Primary peritoneal malignancies are a group of rare cancers involving the lining of the abdominal cavity. Cancers in this category include pseudomyxoma peritonei, cancer of the appendix, and cancer of the ovaries. Treatment of primary peritoneal malignancies is a highly specialized field and is carried out at only a few centers across the United States. The most effective treatment involves surgical debulking of the tumor followed by intraperitoneal hyperthermic chemoperfusion (HIPEC). Follow-up data show that patients who undergo this treatment live longer and have a better quality of life. The Division of Surgical Oncology at the University of Miami Miller School of Medicine was the first in South Florida to provide HIPEC as part of a comprehensive treatment program for primary peritoneal malignancies.

The Division of Surgical Oncology at the University of Miami Miller School of Medicine, was the first to perform the procedure, an intraperitoneal hyperthermic chemoperfusion (HIPEC) in South Florida. offering abdominal cancer patients a novel therapy that combines heat and chemotherapy. The procedure is administered during surgery and has extended the lives and improved the quality of life to patients with certain types of advanced abdominal cancer who might otherwise have limited treatment options.

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HIPEC at University of Miami

HIPEC is an alternative and innovative method of delivering chemotherapy, which is commonly used to treat many types of cancer, to the body. Unlike traditional chemotherapy that is delivered intravenously, HIPEC delivers chemotherapy directly into the abdomen making it a good option for cancers that originated in or have spread to the abdominal cavity. How does HIPEC work? First, your surgeon removes any visible tumors from the abdomen. Next, HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon. This is because the chemotherapy circulates inside the abdomen, allowing it to reach more places. The goal of HIPEC is to prevent these cells from growing into new tumors and causing

How does HIPEC work?

First, your surgeon removes any visible tumors from the abdomen. Next, HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon. This is because the chemotherapy circulates inside the abdomen, allowing it to reach more places. The goal of HIPEC is to prevent these cells from growing into new tumors and causing First, your surgeon removes any visible tumors from the abdomen. Next, HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon. This is because the chemotherapy circulates inside the abdomen, allowing it to reach more places. The goal of HIPEC is to prevent these cells from growing into new tumors and causing the cancer to return.

What are the benefits of HIPEC procedures?

  • HIPEC allows for a higher concentration of chemotherapy to be delivered into the abdomen more effectively and safer than standard chemotherapy, which is delivered intravenously.
  • This type of chemotherapy is best at killing cancer cells that are too small to be seen with the naked eye.
  • Chemotherapy delivered through HIPEC causes fewer side effects than intravenous chemotherapy. This is because the high concentrations of chemotherapy solution are unable to cross what is known as the peritoneal plasma barrier.
  • Experts say that pairing surgery and HIPEC together may be more beneficial than chemotherapy alone.

Am I a candidate for HIPEC?

Typical HIPEC patients are those with certain Stage IV abdominal cancers. Many are seeking an alternative to traditional chemotherapy or radiation therapy, as these options offer limited success treating advanced abdominal cancers. Patients also may have been told that no other treatment will work, but are still hoping to find a solution.