Pseudomyxoma Peritonei

A build-up of mucus in the peritoneal cavity. The mucus may come from ruptured ovarian cysts, the appendix, or from other abdominal tissues, and mucus-secreting cells may attach to the peritoneal lining and continue to secrete mucus.

Pseudomyxoma peritonei (PMP) is a rare cancer that usually starts in the appendix. The cause of PMP isn’t known.

It’s normally slow-growing and makes a jelly-like liquid called mucin. The mucus may come from ruptured ovarian cysts, the appendix, or from other abdominal tissues, and mucus-secreting cells may attach to the peritoneal lining and continue to secrete mucus.

Despite numerous recent advances in chemotherapy, the overall chance of chemotherapy being curative is still low, and the side effects are difficult for the patient to endure. However, when these cancers are confined to the peritoneal cavity, Hyperthermic Intraperitoneal Chemotherapy (HIPEC) becomes an option for candidate patients.

Many of the cancers treated with HIPEC are diseases treated by multiple disciplines in medicine and surgery. It is important that patients discuss HIPEC therapy with their oncologists and surgeon who can guide their therapy appropriately. Sometimes a referral to a Surgical Oncologist or Gynecological Oncologist performing HIPEC is helpful and necessary early at the time of diagnosis. These doctors can help determine if a patient can benefit from HIPEC and then formulate a comprehensive treatment plan.

Joanne: The HIPEC Procedure for Abdominal Cancer

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